Skip to main content

Overview

Corneal Cross-Linking (CXL) is an advanced, in-office treatment that aims to strengthen and stabilize the cornea, the eye’s transparent outer layer. It is especially effective for conditions like keratoconus and corneal ectasia, where the cornea becomes thin and irregularly shaped. The procedure combines Riboflavin (Vitamin B2) drops and Ultraviolet (UV) light to create cross-links between collagen fibers in the cornea, making it more rigid and preventing further deformation. By halting progression, CXL helps preserve your vision.

Corneal Cross-Linking Treats:

  • Keratoconus (corneal thinning and cone-shaped deformation)
  • Post-LASIK ectasia (corneal instability after LASIK surgery)
  • Progressive corneal ectasia (worsening irregular corneal shape)
  • Frequent prescription changes (unstable vision due to corneal deformation)
  • Contact lens intolerance (discomfort or inability to wear lenses caused by irregular corneal surfaces)
  • Blurred or distorted vision (caused by corneal thinning or irregularity)

How Does Corneal Cross-Linking Work?

Corneal Cross-Linking (CXL) works by strengthening and stabilizing the cornea through the creation of new cross-links between collagen fibers, the structural proteins that maintain the cornea’s shape. In this procedure, Riboflavin (Vitamin B2) eye drops are applied to the corneal surface, where they penetrate and saturate the tissue.

The eye is then exposed to a controlled amount of Ultraviolet (UV) light, which activates the riboflavin. This triggers a chemical reaction that forms new bonds between collagen molecules, increasing the cornea’s rigidity.

Benefits of Corneal Cross-Linking:

  • Stabilizes the cornea to prevent further thinning or deformation
  • Reduces the progression of keratoconus and corneal ectasia
  • Preserves vision by halting disease progression
  • Improves contact lens tolerance for better vision correction
  • Minimizes the need for invasive procedures like corneal transplants
  • Provides a high success rate with long-term results
  • Performed as an outpatient procedure with minimal recovery time

Your Corneal Cross-Linking Session

During your session with Dr. Hu, the epithelial layer of your cornea is carefully removed to enhance the absorption of Riboflavin (Vitamin B2) eye drops into the corneal stroma. Once the cornea is fully saturated, it is exposed to controlled ultraviolet-A (UV-A) light for 30 minutes. This activates the riboflavin, generating reactive oxygen species that create new cross-links between collagen fibers, increasing the cornea’s strength and rigidity. Afterward, a bandage contact lens is placed to protect the cornea and promote epithelial healing, which occurs within a few days.

Side Effects & Recovery

After your corneal cross-linking procedure, you may experience mild discomfort, light sensitivity, and blurry vision as your cornea heals. These symptoms are normal and typically improve within a few days. Dr. Hu will provide medicated eye drops to prevent infection, reduce inflammation, and promote healing. A bandage contact lens will remain in place for a few days to protect your cornea. While full visual recovery can take several weeks, most patients notice gradual improvements in vision stability and comfort.

What Results Can I Expect?

With corneal cross-linking performed by Dr. Hu, you can expect a significant halt in the progression of keratoconus or corneal ectasia. While the procedure aims to stabilize your cornea and prevent vision loss, many patients also notice improved contact lens tolerance over time. It’s important to understand that CXL does not correct refractive errors, so you may still need glasses or contact lenses for clear vision. Dr. Hu will closely monitor your progress to ensure optimal results and long-term eye health.

Corneal Cross-Linking FAQs

Is Corneal Cross-Linking Painful?

CXL is not typically painful, as numbing eye drops are used during the procedure. Some patients experience mild discomfort, light sensitivity, or irritation during healing, which usually subsides within a few days.

How Long Does the Procedure Take?

The entire corneal cross-linking procedure takes about an hour per eye. This includes preparing your eye, applying Riboflavin (Vitamin B2) drops, and exposing the cornea to UV-A light for approximately 30 minutes.

Will I Need to Take Time Off Work or Daily Activities?

You may need to take a few days off work and limit your activities while your cornea heals. During recovery, your vision may be blurry, and light sensitivity is common. Dr. Hu will provide personalized recommendations based on your progress.

Will Corneal Cross-Linking Improve My Vision?

The primary goal of corneal cross-linking is to stabilize the cornea and halt the progression of keratoconus or corneal ectasia. While the procedure does not directly improve refractive errors, many patients report better contact lens tolerance and improved visual quality over time as the cornea becomes more stable.

Schedule Your Consultation

Dr. Jimmy Hu is a board-certified ophthalmologist and fellowship-trained corneal specialist from the prestigious Wilmer Eye Institute at Johns Hopkins Hospital. With years of experience in treating keratoconus and corneal ectasia, Dr. Hu is dedicated to preserving your vision using advanced techniques like corneal cross-linking. If you’re experiencing symptoms or have been diagnosed with these conditions, schedule your consultation today to receive expert care.

Schedule a Consultation

The Future
Looks Clear

Contact Us862-44-LASIK
Contact Us 862-44-LASIK